506144
p53 Activator II, Cell-Permeable
RRRQRRKKRGY-G-KKHRSTSQGKKSKLHSSHARSG, RI-TATp53C′-WT, D-isomer, Retro-Inverso p53C′ Peptide, D-isomer
Para informações, por favor, contate o nosso Serviço de Atendimento ao Cliente
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefone: +49 6151 72-0
Fax: +49 6151 72 2000
31 Julho 2010
carregando
| Nº de produto | Tamanho |
|---|---|
| 506144-500UG | 500 μg |
A cell-permeable and proteolytically stable p53-activating peptide that displays antitumor properties. Activates p53-dependent gene transcription and inhibits tumor cell proliferation in a p53-dependent manner, while exhibiting no effect on the proliferation of normal cells expressing wild-type p53. Shown to be effective in suppressing tumor growth in several murine cancer models in vivo. The functional half-life of this peptide has been estimated to be greater than 7 days in murine TA3/St mammary carcinoma cells.
| Informações sobre o produto | |||
|---|---|---|---|
| Peptide Sequence | H-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Gly-Tyr-Gly-Lys-Lys-His-Arg-Ser-Thr-Ser-Gln-Gly-Lys-Lys-Ser-Lys-Leu-His-Ser-Ser-His-Ala-Arg-Ser-Gly-OH | ||
| Form | White lyophilized solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Hygrocopic | Sim | ||
| Packaged under inert gas | Sim | ||
| Purity | ≥95% by HPLC | ||
| Fórmula Química | C166H293N73O45 | ||
| Informação de estoque e transporte | |||
|---|---|---|---|
| Armazenagem | -20°C | ||
| Ship |
Shipped with Blue Ice or with Dry Ice
Standard Handling |
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