506132
Pifithrin-α
2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone, HBr
Para informações, por favor, contate o nosso Serviço de Atendimento ao Cliente
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefone: +49 6151 72-0
Fax: +49 6151 72 2000
31 Julho 2010
carregando
| Nº de produto | Tamanho |
|---|---|
| 506132-10MG | 10 mg |
| 506132-5MG | 5 mg |
A cell-permeable chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes and reversibly blocks p53-mediated apoptosis. Inhibits p53-dependent growth arrest of human diploid fibroblasts in response to DNA damage but has no effect on p53-deficient fibroblasts. Protects normal tissues from the deleterious side effects of chemotherapy. Has been reported to protect neurons against β-amyloid peptide and glutamate-induced apoptosis.
| Informações sobre o produto | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Primary Target | PS3 | ||
| Protect from Light | Sim | ||
| Packaged under inert gas | Sim | ||
| Cell permeable | Sim | ||
| Reversible | Sim | ||
| Purity | ≥95% by HPLC | ||
| Fórmula Química | C16H18N2OS·HBr | ||
| Número CAS | 63208-82-2 | ||
| Informação de estoque e transporte | |||
|---|---|---|---|
| Armazenagem | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
